Personalized dosimetry in minutes
Each patient responds differently to treatment, and serial radionuclide imaging provides patient specific information about the individual radiopharmaceutical kinetics in tumors and normal organs after administration.
The most complete voxel dosimetry software on the market
Hermia Voxel DosimetryTM can be used for a wide range of therapy and imaging isotopes—helping make personalized therapy a reality for your clinical practice. It is regulatory-cleared in Europe, Canada and the US.*
ONE WORKFLOW FOR ALL YOUR DOSIMETRY WORK
Process DICOM images from all camera manufacturers using the same workflow with automatic alignment of multiple SPECT/CT or PET/CT time points including deformable registration.** Cumulated activity in each voxel is calculated at the voxel or organ level, and a Monte Carlo algorithm simulates photon absorption and scatter through the patient’s CTto calculate dose deposition over the entire field of view. Draw regions with automatic organ segmentation** or versatile manual drawing and editing tools. Visualize the calculated total absorbed dose distribution, dose volume histograms and dose results table.
Review of the 3D dose map with automatic organ regions and dose volume histogram analysis.
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Automatic Organ Segmentation
Save time with automatic** liver, kidneys, spleen and lungs segmentation using the patient’s CT.
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Pure theranostic approach
Support for a wide range of therapy and imaging isotopes:*** Ac-225; At-211; F-18; Ga-68; Ho-166; l-123; l-124; l-131; ln-111; Lu-177; Pb-203; Pb-212; Ra-223; Tc-99m; Y-90; Zr-89.
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Validated Monte Carlo Algorithm
Extensive clinical validation of the accuracy of the dose results in patients and phantoms is published in peer reviewed journals (1-5).
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Single time point dosimetry
Apply an effective half-life per organ,** use the Hänscheid method (6) or assume physical half-life to calculate doses from only one imaging time point post-therapy.
Hermia Voxel Dosimetry
Personalised Theranostics for Good Clinical Practice in RPT
”Theranostic dosimetry software has progressed in leaps and bounds
in recent years. Once the preserve of researchers with complicated
spreadsheets requiring hours of processing time per patient, dosimetry can, and must, now enter the clinical mainstream. We owe it to
the patients to optimise this powerful tool in the fight against cancer."
Tom Francke, Assoc. Prof, CEO of Hermes Medical Solutions
Personalized Dosimetry is Essential for NETs
Peptide receptor radionuclide therapy (PRRT) is a powerful tool in the fight against neuro-endocrine tumors (NETs). But the complexities of tailoring the treatment to each individual patient present a challenge to both clinical departments and software companies. In this article we describe a multi-disciplinary effort to overcome the challenges and deliver the optimal treatment for patients.
The Concept of Voxel Based Dosimetry
References
- Hippeläinen E Tenhunen M Maenpaa H Heikkonen J Sohlberg A. Dosimetry software Hermes Internal Radiation Dosimetry. Nuclear Medicine Communications 2017, vol: 38 (5) pp: 357-365
- E. Hippeläinen: Voxel-level dosimetry of 177Lu-octreotate: from phantoms to patients, University of Helsinki, Report Series in Physics, 2017, HU-P-D255
- Heikkonen, J, Maenpaa, H, Hippeläinen, E, Reijonen, V, Tenhunen, M. Effect of calculation method on kidney dosimetry in Lu-177-octreotate treatment. Acta Oncologica 2016; 55:9-10:1069-1076
- Hippeläinen E, Tenhunen M, Maenpaa H, Sohlberg A. Quantitative accuracy of 177Lu SPECT reconstruction using different compensation methods: phantom and patient studies. EJNMMI Research 2016, 6:16
- Hippeläinen E Tenhunen M Sohlberg A. Fast voxel-level dosimetry for 177Lu labelled peptide treatments. Physics in Medicine and Biology 2015, vol: 60 (17) pp: 6685-6700
- Hänscheid H, Lapa C, Buck AK, Lassmann M, Werner RA. Dose Mapping After Endoradiotherapy with 177Lu-DOTATATE/DOTATOC by a Single Measurement After 4 Days. J Nucl Med. 2018 Jan;59(1):75-81
*In the US, Voxel DosimetryTM only allows voxel-based dose calculations for patients who have been administered with radioisotopes. **May be subject to regulatory clearance in your market. Pending 510(k) review, not available for sale in the US. ***In the US, only intended for calculating dose for FDA approved radiopharmaceuticals for any clinical purpose, and calculation of unapproved drugs can only be used for research purposes
Request more info or a demonstration
We would be happy to show you the many possibilities offered by HERMIA through a demonstration or to answer any questions you might have.
To support all your clinical workflows
Browse to read more about all the many possibilities offered by Hermia– our ALL-IN-ONE state-of-the-art software suite. You can pick and choose the specialities and tools adapted to your current clinical needs and scale up whenever new possibilities arise.
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Organ Dosimetry
Organ Dosimetry™ provides a seamless workflow, enabling the user to perform all steps using only one interface.
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OLINDA
OLINDA/EXM® is the most widely used software for standardized dose calculations for diagnostic and therapeutic radiopharmaceuticals.
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Theranostics
Theranostics is a very promising personalized approach to treating cancer, using diagnostic imaging to identify if target receptors are present on cancer cells, followed by precision internal radiation treatment that targets these receptors.
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SPECT reconstruction
Hermia's SPECT reconstruction is optimized for speed and a wide range of procedures, radio-pharmaceuticals and collimators, making it possible to improve image quality while reducing dose and acquisition time from all your SPECT/CT cameras.